By American College of Chest Physicians
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Indd 22 Pulmonary Vascular Diseases (Moores) 7/10/09 8:03:53 PM sensitivity and predictive value to rule out DVT in patients with a low or moderate clinical probability. The false-negative result rate is too high to be useful in patients with a high clinical probability. In those patients and in any patients in the low-risk or moderate-risk groups who have an abnormal d-dimer level, imaging of the extremity is necessary. The “gold standard” imaging test for DVT is compression ultrasound. The diagnosis of DVT using compression ultrasonography is made by findings such as abnormal compressibility or lack of compressibility of the vein and abnormal Doppler color flow study results.
Patients with PH resulting in marked limitation of physical activity. These patients are comfortable at rest, but less than ordinary physical activity causes undue dyspnea or fatigue, chest pain, or near syncope. Patients with PH resulting in inability to perform any physical activity without symptoms. These patients manifest signs of right-heart failure. Dyspnea and/or fatigue may be present at rest, and discomfort is increased by any physical activity. *Modified from the NYHA classification of patients with cardiac disease.
New pulmonary therapies for CF. Curr Opin in Pulm Med 2007; 13:541–546 A very current and concise review of new approaches to the management of CF, including gene therapy, CFTR modulation, manipulation of ion channels, and other antiinflammatory and antiinfective medications. Swensen SJ, Hartman TE, Williams DE. Computed tomographic diagnosis of Mycobacterium avium-intracellulare complex in patients with bronchiectasis. Chest 1994; 105:49–52 A clinical study of 100 patients with bronchiectasis with chest CT scan evidence of MAC infection suggests that the presence of multiple small lung nodules on CT scans is predictive of the presence of MAC on culture.
ACCP pulmonary medicine board review by American College of Chest Physicians